Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
2.The Tianjin Explosions
Under these conditions, he argues, the Fed cannot only trigger crises itself; it can also increase the vulnerability of EMs to crises provoked by other factors.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
最佳乐队组合：Little Big Town
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Flying during the holidays takes special strategies, which we’ve outlined here. It also means being prepared for significant weather delays, especially in the Northeast and Midwest.
Statistics showed that Tibet had around 590,000 rural poor by the end of 2015.
A person walks through snow Tuesday in Belington, West Virginia. Superstorm Sandy buried parts of West Virginia under more than a foot of snow on Tuesday.
Trends and targets in antiviral phototherapy
The University of Tokyo (22nd) and Kyoto University (35th) have maintained their positions as the leading universities in Asia.
7) Let Me Play Devil’s Advocate: Looking for a subtle way to critique? Turn the conversation into an exercise where you’re a detached party performing a function: Poking holes in the logic and plan of attack. You use this strategy to stress test ideas without making the process personal.
I am here to speak for the countless animals dying across this planet because they have nowhere left to go. We cannot afford to be not heard. 我为这个行星上无数正在垂死的动物而演讲，因为它们几乎已经无处容身了。
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
What growth dollar exports did see among major trading partners came from shipments to the US, which rose 5.5 per cent year on year to $37.06bn. Exports to South Korea also showed growth of 8.3 per cent to $10.2bn.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
4) I’m On It: You’re giving your full attention. You’re saying, “Relax. Don’t worry about a thing. I’ll see to it personally.” That response can disarm just about anyone. To express a deeper commitment, use “You have my word.” This makes you more accountable to someone, conveying that you’re on board and will make it happen…whatever it takes.
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
我们从中精选了110部新剧和回归剧，又进一步缩减到下面的20部剧（内中没有包括HBO台的《真探》[True Detective]，因为它被移到今年晚些时候，亦不包括《权力的游戏》[Game of Thrones]、《副总统》[Veep]和《硅谷》[Silicon Valley]，其中《硅谷》将在四月播出第一集，具体日期未宣布）。从《绝命毒师》(Breaking Bad)的衍生剧到《小镇疑云》(Broadchurch)的回归，再到《火线警探》的最终季，冬天真是电视剧迷的好时光。
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Ninety percent of the students believe their universities' guidance on entrepreneurship would help their future businesses. In addition, they professed appreciation for policies intended to encourage entrepreneurship.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
在针对已拥有金融业工作经验的学员开设的金融课程的排行榜上，伦敦商学院(London Business School)重新夺回在2011年至2015年占据的冠军宝座，同时英国剑桥大学(University of Cambridge)佳奇管理学院(Judge Business School)跌回第二名。
I wish you a happy New Year. All affection and best wish
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
It is not unusual for the documented wealth of China’s richest people to surge suddenly — or even for previously unknown tycoons to burst into prominence — as stock exchange listings and other public investments thrust them into the spotlight.
Influenza neuraminidase: A druggable target for natural products
THE EFFECT OF RAPID CHANGE
差不多人人都知道谷歌的分析工具Google Analytics，但是你是否用过谷歌的网站管理员工具(Google Webmaster Tools)？作为一名营销人员，我认为谷歌的网站管理工具是我用过的最重要的免费工具之一。你肯定想让自己公司的名字出现在谷歌搜索结果之中，对吧？那么为什么不听听谷歌网站管理员工具教给你的诀窍呢？
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Second, McDermott, a career 39.9% three-point shooter, addresses Oklahoma City's biggest roster weakness—a lack of perimeter options around Russell Westbrook—and remains on a bargain rookie deal through the end of next season.
The role of biosensors in the detection of emerging infectious diseases
There are 15 Chinese brands in the top 100, one more than last year and a sharp rise on a decade ago, when China Mobile was the only Chinese brand.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Third, McDermott provides some protection against the possibility of Andre Roberson departing as a free agent in the summer.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
The Wizards need to surge ASAP if they want to stay in this. We saw what happened last year when they waited too long to get it together.
Interestingly, BRICS bloc has reduced their exposure to these securities at a time when America's economic activity is expanding at a moderate rate.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
She said: "I am extremely surprised and overwhelmed. I just want to start by saying what an incredible year for women in film. These categories are so crowed and crammed with incredible integrity and skill and I feel prouder than ever to be included."
约瑟夫?斯蒂格利茨(Joseph Stiglitz)等诺贝尔经济学奖得主、比尔?麦吉本(Bill McKibben)等环保活动人士、乔治?索罗斯(George Soros)及新经济思维研究所(Institute for New Economic Thinking)、阿尔?戈尔(Al Gore)和其他现代思想家全都提醒我们，传统经济学家（以及他们效力的银行、企业和政府机构）都已对坏的经济学理论成瘾，他们在破坏美国的未来。
其他入围者分别是：《失去信号：黑莓离奇崛起与惊人陨落背后不为人知的故事》(Losing the Signal: The Untold Story Behind the Extraordinary Rise and Spectacular Fall of Blackberry)，作者杰基麦克尼什(Jacquie Mcnish)和肖恩缠尔科夫(Sean Silcoff)回顾了黑莓是怎样偏离了航向；《数字黄金：比特币背后不为人知的故事》(Digital Gold: The Untold Story of Bitcoin)，作者纳塔涅尔波佩尔(Nathaniel Popper)审视了虚拟货币比特币的崛起；《音乐如何变免费：一整代人犯下同样罪行的后果》(How Music Got Free: What Happens When an Entire Generation Commits the Same Crime?)，作者斯蒂芬威特(Stephen Witt)介绍了盗版和对等网络共享(P2P)扰乱唱片业的历史；《做不完的事：女人、男人、工作、家庭》(Un滻椀猀栀攀搀 Business: Women Men Work Family)，作者安妮-玛丽斯劳特(Anne-Marie Slaughter)在书中讨论了实现性别平衡面临的挑战，以及《行为不端：解读行为经济学》(Misbehaving: The Making of Behavioural Economics)，作者理查德泰勒(Richard Thaler)追踪了行为经济学的发展。
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
值得注意的是，本年度传播假消息之首的网站域名当属“abcnews.com.co.” 在十一月的一次Verge的采访中，伊利诺伊州大学信息科学学院的Nicole A. Cooke教授引用了一个假新闻网站上的消息，这个假新闻网站使用的是危险和普遍的策略，即域名和真网站看上去只有微小的区别。他们让消息源从第一眼看上去具备真实性。管理abcnews.com.co的人告诉华盛顿邮报，他相信他的网站在特朗普大选期间充当了一个重要的因素。
People in fourth-tier and smaller cities have economic pressures close to the national average level in terms of income, education, medical services and elderly care, while family and human relationship stress are higher than second- and third-tier cities.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
In the past decade, only three blue diamonds of 10 carats or more with the same vivid grading for intensity have been sold at auction, all weighing less than 12 carats and none flawless, he said.
Chances are if you are lucky enough to have a job, the thought of quitting sounds ridiculous. With the unemployment rate at an all time high, most people are thanking their lucky stars to be employed.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Marvel created superhero Blue Ear, who wears a hearing aid, after a little boy refused to wear one because "superheroes don’t wear hearing aids".
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
He slipped a note through the door with the message "People stuck inside, please ask the property management for help," and hoped someone would pick it up and act on it.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
他在最后一刻选择了教育慈善机构Teach First，后者如今已经成为英国招聘新毕业生最多的机构。雷文斯克罗夫特没有空降至需要重组的公司，而是开始在波尔主教学校(Cardinal Pole School)教授商业和经济学，该校主要招收伦敦东部哈克尼区(Hackney)11岁至19岁之间的青少年。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Despite the solid expansion, the yearly rate weakened to -1.4 per cent last month, from a -0.8 per cent pace in September. Economists expected production to have declined 0.9 per cent over the 12 months to October.
The proposed amendment, which is expected to come into force on Jan 1, contains a clause stipulating extended maternity leave and other welfare for couples having children. These are expected to boost the willingness of some couples to have a second child. Many couples have expressed reluctance to have a second child because of the high costs of bringing-up two children and the prejudice they anticipate from employers.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The mainstream remains the awkwardly named sector of Massively Multiplayer Online Role Playing Games, or MMORPGs. In October, six out of the 10 most popular online games in China are MMORPG games, according to the report. World of Warcraft by Activision Blizzard, Inc. (ATVI) still tops the list with the most registered players and peak simultaneous online users. But the current government regulatory fighting over its Chinese license, held by Netease.com Inc. (NTES), may yet have a negative impact on the game, according to the report.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
In a sign that civil service jobs may be losing their appeal, a report issued by recruitment website Zhaopin in late March said more than 10,000 public sector employees, including civil servants and staff members at public institutions, had submitted their resumes to potential employers through the site in just two months. The number was 34 percent higher during the same period last year, the report said.
However, the economists polled expect slightly higher growth rates and substantially higher inflation over 2016.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
●"Cinnamon Roll Can Explodes Inside Man’s Butt During Shoplifting Incident"
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
You are so engaged in thinking of him that you don't notice that there is no No.12.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The gorgeous Birman cat has more than 128,000 Instagram followers. And it has been the inspiration for many of Lagerfeld's designs.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Warriors winning title was inevitable
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
“These kinds of questions are really front and center, even though they’re not necessarily verbalized.”
China's online retail volume is expected to outperform the rest of the world by reaching four trillion yuan (618 billion USdollars) this year, Commerce Minister Gao Hucheng said Sunday.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Drama Series: “Game of Thrones” (HBO)
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Stripping out price, volumes of Chinese imports in October fell a more modest 2.6 per cent from a year earlier, according to estimates from Oxford Economics.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
On the occasion of the New Year, may my wife and I extend to you and yours our warmest greetings, wishing you a happy New Year, your career greater success and your family happiness.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Makers of processed food, soda and fast food see markets in the developing world as their greatest growth opportunities. At the same time, obesity rates and weight-related illnesses are on the rise in developing countries. An ongoing series of articles examined the interaction of these two trends, starting with cases in Brazil, Ghana and Colombia. Taken together, these stories reveal “a new global food order, and a new health crisis.”
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
In 2012, Google introduced Google Glass, a computer you can wear on your face. Someone wearing the glasses can be walking down the street or doing any everyday task while simultaneously seeing an overlay of calendar appointments, messages, and subway alerts. They can make video calls and even upload live videos to the Internet while on the move, without ever needing to use their hands. Google Glass might be cool, it might be new, it might be revolutionary, but it's definitely not the first pair of wearable computer glasses.
Overall, starting a company ranked lowest among reasons cited for undertaking an EMBA (rated 5.5 out 10). Students’ main motivations were learning about management (9.1), networking (8.3) and increasing earnings (8.1).
And, men are 2.8 times more likely to use this obvious phrase than women.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
What dangers does the Fed present to EMs today? One of the biggest risks, says Mr Koepke, is that it might “get behind the curve” and delay raising rates for too long. This would result not only in a surprisingly big hike when it came, but also a higher terminal interest rate than would otherwise be the case.
Historians now hope to dispel some of the myths about Richard, publicising evidence to refute claims that he killed the two young princes and focusing on what he achieved in his brief two-year reign, including the establishment of a system of bail and legal aid.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
More than 350,000 gamers from across Europe (and some from North America and Asia) have made the annual pilgrimage to the quaint German city of Cologne, which has a population of just over 1 million. Activision used the convention to debut its multiplayer gameplay for Sledgehammer Games’ Call of Duty: Advanced Warfare, allowing attendees hands-on access to the November 3 release.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
But when you think of fields where there just aren't enough skilled candidates to go around, one that probably doesn't come to mind is supply chain management: The complicated, behind-the-scenes work of getting goods from one place to another, on time and on budget.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Turn your work in on time. If extra credit work is offered, do that too.
Anti-HIV drug repurposing against SARS-CoV-2
This is the sixth edition of the QS World University Rankings by Subject, featuring a record-breaking 42 disciplines, making it the largest-ever ranking of the kind. The expert opinion of the world's top 76,798 academics and 44,426 employers informed the results, alongside the analysis of 28.5 million research papers and over 113 million citations sourced from the Scopus/Elsevier bibliometric database, said QS.
当晚的最大赢家可能还要属主持人蒂娜?费和埃米?珀勒，这是两人第二次搭档主持金球奖颁奖典礼，且她们今年表现丝毫不逊去年，创下了1,970万观众的六年来最高收视率。金球奖颁奖典礼由好莱坞外国记者协会(Hollywood Foreign Press Association)举办，举办地点位于加利福尼亚州贝弗利山庄的贝弗利山希尔顿酒店(Beverly Hills Hilton)。
Length-scale dependence of protein hydration-shell density
The Shanghai Composite is nursing a decline of 6.85 per cent, while the tech-focused Shenzhen Composite is down 8.19 per cent.
Curry scored 27 points and the defending champions moved within one victory of matching the best start in NBA history, holding off the Chicago Bulls 106-94 on Friday night to improve to 14-0.
《纸牌屋》(House of Cards)，Netflix，2月27日播出。Netflix的政治大戏，第三季有13集。除凯文·斯派西(Kevin Spacey)与罗宾·怀特(Robin Wright)外，曾出演《忧愁河上桥》(Treme)的基姆·迪金斯(Kim Dickens)亦加盟该剧，“Pussy Riot”的两位成员亦有客座出演。
But as economic growth slows in China, institutional investors from further afield say the city’s property market has overheated and is entering a correctional phase.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Baby Driver recently placed on the National Board of Review’s Top 10 list. The film holds a 93% on Rotten Tomatoes and took in over $100 million dollars at the box office.
Coming of age: in the modern banlieues of Paris and in San Francisco in the 1970s. These movies dramatize the harrowing, thrilling passage to womanhood with unsparing honesty and infinite compassion.
About this collection